Compile Data Set for Download or QSAR
maximum 50k data
Found 18 of affinity data for UniProtKB/TrEMBL: Q9Z2J6
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356677(CHEMBL1917592)
Affinity DataKi:  0.370nMAssay Description:Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356669(CHEMBL1917584)
Affinity DataKi:  2.40nMAssay Description:Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM21610(2-[(3R)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)
Affinity DataKi:  5nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50442299(CHEMBL2442750)
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-prostaglandin D2 from mouse CRTh2 receptor expressed in CHO cells after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM21603(2-[(3R)-5-chloro-1'-[(2-fluorophenyl)methyl]-1,2-d...)
Affinity DataKi:  22nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]PGD2 from mouse CRTh2 receptor expressed in K562 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM21605(2-[(3R)-5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-d...)
Affinity DataKi:  33nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50356646(CHEMBL1917389)
Affinity DataKi:  37nMAssay Description:Displacement of [3H]PGD2 from mouse CRTH2 expressed in human HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM21611(2-[(3S)-5-chloro-1'-[(5-chloro-2-fluorophenyl)meth...)
Affinity DataKi:  88nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM21543(2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  150nM ΔG°:  -38.6kJ/molepH: 7.4 T: 2°CAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM21597(2-{1'-benzyl-5-chloro-1,2-dihydrospiro[indole-3,3'...)
Affinity DataKi:  480nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50344991(2-(4'-(ethylsulfonyl)-2'-methyl-5-(trifluoromethyl...)
Affinity DataIC50:  1nMAssay Description:Binding affinity to mouse CRTh2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50200271(4-bromo-2-(1-phenyl-1H-pyrazole-4-carbonyl)phenoxy...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50312906(2-(2-(bis(4-fluorophenyl)methyl)-4-(3-fluorophenyl...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50006830(CHEMBL3236948)
Affinity DataIC50:  4nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50401097(CHEMBL2204469)
Affinity DataIC50:  7nMAssay Description:Inhibition of mouse CRTH2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50442299(CHEMBL2442750)
Affinity DataIC50:  94nMAssay Description:Antagonist activity at mouse CRTh2 receptor expressed in CHO-K1 cells assessed as inhibition of [125S]-GTP-gamma-S binding after 50 mins by liquid sc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

Curated by ChEMBL
LigandPNGBDBM50296848(2-(1-(3,4-difluorophenylsulfonyl)-2-methyl-1H-pyrr...)
Affinity DataIC50:  167nMAssay Description:Antagonist activity against mouse CRTh2 receptor expressed in K562 cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed